p16, cyclin D1 and Rb expression in colorectal carcinomas: Correlations with clinico-pathological parameters and prognosis
نویسندگان
چکیده
منابع مشابه
p16, cyclin D1 and Rb expression in colorectal carcinomas: Correlations with clinico-pathological parameters and prognosis.
In an immunohistochemical study, 200 colorectal carcinomas were stained with monoclonal antibodies recognizing the cell cycle regulators p16, cyclin D1 and Rb, in order to study their expression and prognostic impact. Cyclin D1 and Rb were generally expressed in a nuclear pattern, whereas p16 also exhibited cytoplasmic reactivity. Immunoreactivity was observed in 94% (p16), 75% (cyclin D1) or 9...
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ژورنال
عنوان ژورنال: Molecular Medicine Reports
سال: 2008
ISSN: 1791-2997,1791-3004
DOI: 10.3892/mmr.1.1.27